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Linda Ball

Linda Ball
Science and research
My bio:

M.A. Hons. (Oxon) Natural Sciences, Chemistry, University of Oxford, UK
PhD (Cantab) Natural Sciences, Biochemsitry and Biophysics, University of Cambridge, UK

Research areas:
High resolution 3D structure determination and functional investigations of biomolecules and their complexes, wherever possible in near-native solution conditions. Main focus on families of proteins and small molecules of direct medical interest (potentially druggable targets).
• Main biophysical methods: NMR spectroscopy, X-ray, EXAFS, CD, UV, AUC, ITC, Biacore, thermofluor, fluorescence, SPOT array analsyis.
• Main biological/biochemical methods: bio-informatics, plasmid design, overexpression and purification of recombinant proteins, electrophoresis methods, blotting, binding assays, mutational analysis.
• Development and implementation of functional assays for protein families
• Fragment based screening and structure-based optimization of small molecules for modulating protein function using NMR, molecular modelling, SPOT analysis, mutational analysis
• Recent research areas: epigenetics, chromatin dynamics, signalling, apoptosis, biofilms

Languages: English (native), German (business fluent), Italian (basic), French (basic).

Other experience:
Research group leader / Principal Investigator in Molecular Biophysics and Biomolecular NMR,
Project Management, Recruitment and Team Building, Budget Management and Fund-raising, Networking and Collaboration Building, Presentation and Communication
Reviewer for many scientific journals, evaluator of scientific publications for F1000 Biology,
Founder Member of the Protein Modules Consortium ( and the original Oxford Module Consortium (